The search space for protein engineering grows exponentially with complexity. A protein of just 100 amino acids has 20^100 ...

This article and associated images are based on a poster originally authored by Marina Fedorova and Ian Hiles and presented at ELRIG Drug Discovery 2024 in affiliation with GSK. This poster is being ...

The search space for protein engineering grows exponentially with complexity. A protein of just 100 amino acids has 20100 ...

MIT researchers have built an AI language model that learns the internal coding patterns of a yeast species widely used to ...

Gas vesicles are among the largest known protein nanostructures produced and assembled inside microbial cells. These hollow, ...

The cost-effective, easy-to-use T7 expression system has been integral to Escherichia coli protein production since its introduction in 1986. Now, a just-developed enhancement is making it even better ...

Carfilzomib prevented BCMA degradation, increased target density, and improved CAR T susceptibility by ~26%–28% in vitro, while enhancing xenograft antitumor activity without worsening T-cell ...

To enhance CAR T therapies, scientists are actively studying TCR signaling and T-cell exhaustion mechanisms to improve CAR T persistence and function. Additionally, there is a growing trend towards ...

Digital Pathology–Based Multimodal Artificial Intelligence Scores and Outcomes in a Randomized Phase III Trial in Men With Nonmetastatic Castration-Resistant Prostate Cancer FGFR2b protein ...

Researchers identified three age-related proteins that may play key roles in PH progression as possible treatment targets.