Deep in the folds of the intestine, in microscopic pockets called crypts, a quiet surveillance system is always at work. Stem ...

Two related studies from the University of California, Riverside, have reported that reduced activity of the PTPN2 gene weakens intestinal defences, allowing harmful Escherichia coli strains to ...

A key protein expressed in epithelial “skin” cells plays a critical role in protecting the structure and function of cells in the nervous system of a model nematode, a type of worm, according to new ...

A fundamental challenge for cystic fibrosis (CF) gene therapy is ensuring sufficient transduction of airway epithelial cells to achieve therapeutic correction. Gene editing is a method to permanently ...