Gene expression is linked to RNA transcription, which cannot happen without RNA polymerase. However, this is where the similarities between prokaryote and eukaryote expression end. Central to the ...

Also, as the prokaryotic cell lacks a clearly defined nucleus and both transcription and translation takes place in the cytoplasm, there is no need to transport the mRNA to the cytoplasm after ...

The regulation of mRNA transcription plays a key role in relaying signals from the environment and during development into the gene expression program of a cell. During transcription initiation, a ...

All modern organisms fall into two classes, eukaryotes and prokaryotes. Eukaryotes (from the Greek meaning “true kernel”) have a cell nucleus that harbours most of the cell’s genetic information and ...

DNA methylation refers to the process of adding a methyl group to specific regions of DNA. This process can bring about changes in the activity of DNA without changing the sequence of nucleotides.

Researchers have revealed new details about the CRISPR-Cas5-HNH/Cascade complex, a variant of the type I-E CRISPR-Cas system, providing insights into its DNA recognition and cleavage mechanisms. The ...

A newly discovered promoter element "start" points to a shared regulatory syntax for controlling transcription initiation in ...

The Royal Swedish Academy of Sciences has awarded the Nobel Prize in Chemistry for 2006 to Roger D. Kornberg of Stanford University "for his studies of the molecular basis of eukaryotic transcription.

Prokaryotic cells, which include all bacteria and archaea, are ancient, and relatively simple compared to eukaryotic cells, which are found in fungi, plants, and animals. Scientists have long sought ...

Proteins are essential biological molecules that perform a vast array of functions crucial for life, from catalyzing ...

Modern eukaryotic cells have proteins that enable chromosome segregation during cell division, new discoveries shed light on their origin in simpler prokaryotic organisms. Modern nucleated (eukaryotic ...