One of the main challenges for tuberculosis (TB) therapy is how to deliver drugs to the site of disease. Once the body’s immune system is infected with tuberculosis, it forms granulomas—tight clusters ...

Background: Granulomas were frequently misdiagnosed as peripheral lung cancers (PLCs) due to their similarities in imaging findings. This study aimed to establish a classification system based on thin ...

Pulmonary sarcoidosis is a condition that causes tiny groups of immune cells to clump in your lungs. These groups of cells form swollen, inflamed lumps called granulomas. Granulomas can make it hard ...

Neutrophils induce anti-inflammatory -- or M2 -- macrophages deep in their granulocyte core. The dense globular structures of granulomas in animals, particularly in the lungs, have been studied.

A proof-of-concept trial shows novel sarcoidosis PET/CT tracer detects inflammatory activity, supporting further clinical ...

Treatment beyond RECIST-defined progression in relapsed EGFR-mutated non-small cell lung cancer (NSCLC) patients treated with 2nd line osimertinib. Phase Ib study of sintilimab in combination with ...

XTMAB-16 is an anti-TNFa monoclonal antibody currently under investigation. Based on its ability to block TNFa, XTMAB-16 may disrupt an inflammatory pathway and help slow granuloma formation. XTMAB16 ...

BASEL, Switzerland & LONDON & NEW YORK--(BUSINESS WIRE)--Roivant (Nasdaq: ROIV) and Kinevant Sciences, a clinical-stage biopharmaceutical company developing new medicines for rare inflammatory and ...

Histoplasmosis is a fungal infection that can cause swelling, inflammation, and, sometimes, small semi-opaque or calcified nodules on the lungs. However, histoplasmosis does not always cause symptoms.