Peutz-Jeghers syndrome is also called intestinal polyposis-cutaneous pigmentation syndrome. It is an inherited or sporadic condition characterized by the development of hamartomatous polyps in the ...

THE clinical condition described by Peutz, 1 of Holland, in 1921 was characterized by him as a remarkable situation of familial polyposis of the mucosa of the small intestine with unusual skin and ...

What is the optimal management of residual small bowel polyps in a young woman with Peutz-Jeghers intestinal polyposis? She has had repeated small bowel resections for bowel necrosis after ...

PJS is an autosomal dominant inherited disorder characterized by mucocutaneous pigmentation, hamartomatous gastrointestinal polyps and cancer predisposition. Although Peutz first recognized the ...

Peutz-Jeghers syndrome (PJS) is a familial cancer disorder due to inherited loss of function mutations in the LKB1/ STK11 serine/threonine kinase. PJS patients develop gastrointestinal hamartomas with ...

LKB1 appears to act upstream of PAR1A in a kinase cascade, and we have determined the sites at which PAR1A is phosphorylated downstream of LKB1. These sites are required for PAR1A activity, but LKB1 ...

PJS is a dominantly inherited cancer syndrome characterized by the presence of multiple intestinal polyps and a high risk for cancer 1,2. Most cases of PJS involve inactivating germline mutations in ...

Kou-ichi Jishage, Jun-ichi Nezu, Yosuke Kawase, Takamitsu Iwata, Miho Watanabe, Akio Miyoshi, Asuka Ose, Kiyoshi Habu, Takei Kake, Nobuo Kamada, Otoya Ueda, Michiko Kinoshita, Dieter E. Jenne, Miyuki ...

Based on the Nathaniel Bishop Harman Prize Essay of the British Medical Association (1956). I am indebted to Mr. J. R. St. G. Stead for allowing me to investigate and publish several cases treated ...

The article If You've Seen Bearded Cops Around Bergen County, There's A Tragic Reason appeared first on Wyckoff Patch. BERGEN ...