Harvard Apparatus has announced the release of the New Pump 11 Elite Glucose Clamp Infusion System for academic euglycemic or hyperglycemic glucose clamp studies. The Pump 11 Elite Glucose Clamp ...

OBJECTIVE: Insulin inhibition of insulin secretion has been described in normal lean subjects. In this study, we examined whether this phenomenon also occurs in the morbidly obese who often have ...

OBJECTIVE: Insulin is thought to be an important regulator of leptin secretion. However, increasing evidence suggests that insulin-mediated glucose uptake rather than insulin per se regulates ...

Objective — To determine the pharmacokinetic and pharmacodynamic dose-response effects of insulin glargine administered subcutaneously in individuals with type 2 diabetes. Research design and methods ...

The experiments reported below concern the effect of a continuous infusion of glucose on the hepatic glucose-6-phosphatase level in rats with different levels of endogenous insulin production and ...

Both fasting plasma glucose (9.3 ± 0.6 vs. 5.2 ± 0.1 mmol/l, P < 0.001), insulin (16 ± 2 vs. 6 ± 1 mU/l, P < 0.01), and C-peptide (1,013 ± 134 vs. 509 ± 50 pmol/l, P < 0.01) concentrations were higher ...

Current Primary Outcome Measures •Plasma glucose (absolute values) (units: mg/dL) [ Time Frame: Up to 425 minutes from the start of the procedure. ] -- Goal is first to clamp insulin infusion rate to ...

THE intravenous administration of potassium chloride with glucose is a common therapeutic measure in cases of potassium depletion. This study was prompted by the appearance of serious ventricular ...