Some genetic mutations that are expected to completely stop a gene from working surprisingly cause only mild or even no symptoms. Researchers in previous studies have discovered one reason why: cells ...

Septins are a conserved family of GTP-binding proteins that assemble into filamentous structures, earning them recognition as the fourth component of the cytoskeleton alongside actin, microtubules and ...

From molecular chaperones to mitochondrial failure, discover how heat reshapes the human transcriptome and drives the biological cascade that links rising temperatures to organ injury and public ...

Cover -- Half Title -- Series Page -- Title Page -- Copyright Page -- Table of Contents -- Series Preface (Evolutionary Cell Biology) -- Preface -- Editor ...

A new study from Whitehead Institute Member Jonathan Weissman reveals how cells may activate a compensation system that can, in some cases, reduce the effects of potentially harmful genetic mutations.

As we age, our cells don’t just wear down—they reorganize. Researchers found that cells actively remodel a key structure called the endoplasmic reticulum, reducing protein-producing regions while ...

RUVBL proteins, comprising highly conserved AAA+ ATPases, serve as essential organisers within numerous multiprotein assemblies that govern critical cellular processes. These proteins are implicated ...

UC Davis researchers Gant Luxton, Daniel Starr and Xiangyi Ding have used tiny fluorescent particles to study what is going on inside the cells of Caenorhabditis worms. They found that the cells are ...

Improvements in public health have allowed humankind to survive to older ages than ever before, but, for many people, these added golden years are not spent in good health. Aging is a natural part of ...

Scientists have transformed RNA, a biological molecule present in all living cells, into a biosensor that can detect tiny chemicals relevant to human health. Research by scientists centers on RNA, a ...

Data integrity is key to the success of any cell therapy program. CDMOs can implement robust data management systems for manufacturing that provide secure, real-time access to data, which can help ...

An international group of researchers led by Pompeu Fabra University has discovered the nanomachine that controls constitutive exocytosis: the uninterrupted delivery of spherical molecular packages to ...