The central nerve system (CNS) plays a crucial central regulatory role in mammalian life, and the blood-brain barrier is the most selective physical barrier protecting the brain by strictly ...
Major advance promises to accelerate the understanding and improved treatment of a wide range of brain disorders, including stroke, cerebral vascular disorders, brain cancer, Alzheimer's disease, ...
The brain is among the most “immune-privileged” of organs primarily through the highly selective permeability of the blood-brain-barrier (BBB), its minimal lymphatic drainage, the presence of ...
Focused ultrasound is just one strategy researchers are using to get drugs into the brain. This article first appeared in The Checkup, MIT Technology Review's weekly biotech newsletter. To receive it ...
Fortress, filter, and gatekeeper: New insights into how the blood-brain barrier safeguards the brain
In a recent primer paper published in the journal Current Biology, researchers elucidated the structure and function of the blood-brain barrier (BBB). It highlights the BBB as a complex, dynamic ...
Leakiness in the brain could explain the memory and concentration problems linked to long COVID. In patients with brain fog, MRI scans revealed signs of damaged blood vessels in their brains, ...
Focused ultrasound with microbubbles is a noninvasive procedure that transiently opens the blood-brain barrier (BBB) using low-intensity sound waves. The openings reseal within 24 hours. Using MRI to ...
Antiamyloid antibodies have been used to reduce cerebral amyloid-beta (Aβ) load in patients with Alzheimer’s disease. We applied focused ultrasound with each of six monthly aducanumab infusions to ...
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