A new study identifies a mechanism that makes bacteria tolerant to penicillin and related antibiotics, findings that could lead to new therapies that boost the effectiveness of these treatments. A new ...

Antibiotic treatment disrupts the balance of beneficial and harmful bacteria in a person's gut. That disruption can lead to the overgrowth of fungal species in the gut mycobiota, including the common ...

Top: β-lactam antimicrobial agents rupture bacteria by destroying their cell walls. Bottom: The red text in the structural formula represents the β-lactam ring, which is essential for bactericidal ...

Surgical antimicrobial prophylaxis using non-beta‑lactams administered before major surgery was independently associated with a significantly higher risk for surgical site infection than conventional ...

It’s a story 30-odd years in the making. The tale begins in the 1990s, when Roche had an anti-infectives unit. Back then, plenty of pharmaceutical companies had scientists working on novel antibiotics ...

Infants of mothers treated in the first trimester of pregnancy with trimethoprim/sulfamethoxazole (TMP-SMX) antibiotics for urinary tract infection (UTI) appeared to ...